Citrulline

Here's a counterintuitive fact: if you want to raise your arginine levels and boost nitric oxide, taking citrulline is actually more effective than taking arginine itself. That's because citrulline bypasses liver metabolism and converts to arginine in the kidneys, resulting in a more sustained and reliable increase in circulating arginine and nitric oxide.

The performance benefits are well-documented. Studies show citrulline supplementation increases time to exhaustion during high-intensity exercise, improves power output, and reduces the perception of effort — meaning the same workout feels easier. It also accelerates the clearance of ammonia and lactate, metabolic byproducts that contribute to fatigue and muscle burn.

Beyond the gym, citrulline supports cardiovascular health through its nitric oxide-boosting effects. Better blood flow means better nutrient delivery, waste removal, and vascular function. It's one of the most evidence-backed ergogenic supplements available, and it works for both strength and endurance athletes.