Melatonin SR
Melatonin Sustained-Release
SUSTAINED-RELEASE SLEEP MAINTENANCE
Melatonin SR (Sustained-Release) gradually releases melatonin throughout the night, mimicking your body's natural production curve. Designed specifically for people who fall asleep fine but wake up in the middle of the night and can't get back to sleep.
30-day supply

Key Benefits
Sustained-release formula for staying asleep through the night
Supports uninterrupted, deep sleep cycles
Gradual melatonin delivery mimics natural pattern
Ideal for those who wake in the middle of the night
Supports These Goals
Linked Biomarkers
Our blood test can measure these markers to personalize your dose
Why you'll love it
Standard melatonin is great for sleep onset — it helps you fall asleep. But your body's natural melatonin doesn't peak and disappear; it maintains elevated levels throughout the night, gradually declining toward morning. If you wake at 2 or 3 AM and can't fall back asleep, a standard melatonin supplement (which is fully absorbed within 1-2 hours) has already come and gone.
Sustained-Release melatonin solves this by using a matrix that gradually dissolves over 6-8 hours, releasing melatonin in a pattern that more closely mimics your body's natural nighttime production. The initial release supports falling asleep, and the continued release supports staying asleep through the second half of the night.
This is particularly beneficial for older adults (whose natural melatonin production is lower and peaks earlier), shift workers adjusting to daytime sleep, and anyone whose middle-of-the-night waking is disrupting their sleep quality. Clinical studies show sustained-release melatonin improves sleep maintenance, increases total sleep time, and enhances next-day alertness compared to immediate-release formulations.
Clinical Evidence
Our recommendations are grounded in published clinical research. Here are key studies supporting the benefits of Melatonin SR.
Slow-release melatonin keeps working for 6 months with no tolerance buildup
Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial
2010
Slow-release melatonin improves sleep quality and next-day alertness in older adults
Efficacy of prolonged release melatonin in insomnia patients aged 55–80 years: quality of sleep and next-day alertness outcomes
2007
Study titles shown are simplified summaries of the original research for readability. Original titles are shown in italics below each heading. All studies cited are from peer-reviewed journals indexed in PubMed. Links open in a new tab to the original source. These studies are provided for informational purposes and do not constitute medical advice.

How much do I really need?
Take one 3mg sustained-release capsule 30-60 minutes before bedtime. Do not crush or chew — the sustained-release mechanism requires the capsule to dissolve gradually. Allow a full 7-8 hour sleep window to avoid morning grogginess from the extended release.
Safety & Transparency
Full transparency — here's exactly what's in every capsule, verified by our manufacturer.
Third-Party Tested
Every batch is independently tested by ISO-17025 accredited labs for purity, potency, and contaminants.
Doctor Formulated
Designed by healthcare professionals using evidence-based research and clinical expertise.
cGMP Certified
Manufactured in cGMP & UL certified, FDA-registered facilities with a flawless inspection record.
Important Information
Contraindications:
- •sedative medication
- •autoimmune condition
Not suitable for:
- •pregnant
- •breastfeeding
May cause drowsiness — allow a full 7-8 hours for sleep. Not recommended with sedative medications, for those with autoimmune conditions, or during pregnancy/breastfeeding.
As with any natural health product, you should consult your healthcare practitioner on the use of this product. Store product in a cool and dry place. Keep out of reach of children. If you experience an adverse event or allergic reaction, discontinue use immediately and contact a healthcare professional.
Still not sure what you need?
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